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A comparison of the biological activities of ethyl acetate fractions from the stems and leaves of
Zhaolei WANG, Kai JIANG, Qinchao DING, Shujun LIU, Xiaobing DOU, Bin DING
《农业科学与工程前沿(英文)》 2020年 第7卷 第4期 页码 505-512 doi: 10.15302/J-FASE-2019271
Pursh (PCP) is a popular traditional medicinal plant in China, widely used for the treatment of a variety of liver diseases. Although it has been long recognized that the main active elements of PCP are contained in ethyl acetate fraction (EAF), little is known so far in terms of the relative effectiveness of EAF derived from the stems versus leaves of this plant. In the current study, we prepared EAF by reflux extraction and sequential extraction from the stems (SEAF) and leaves (LEAF) of PCP and tested their hepatoprotective efficacies. The extract rates and flavonoid contents of LEAF were higher than those of SEAF. EAFs (>50 μg·mL ) prevented lipid accumulation in cells and protected against lipotoxicity injury when the concentration exceeded 25 μg·mL . More than 95% free radicals released by 2,2-diphenyl-1-picrylhydrazyl (DPPH) were eliminated by 25 μg·mL SEAF and 50 μg·mL LEAF, respectively. Further, EAFs (25 μg·mL ) also showed protective antioxidant effects, with the activity of LEAF being significantly higher than that of SEAF. EAFs (10 mg·mL ) also showed similar unspecific bacteriostatic activity. In comparison with SEAF, LEAF contained more flavonoids and had a higher anti-oxidation capability and for these reasons we suggest it should be better for clinical use.
关键词: antibacterial anti-oxidation lipid accumulation lipotoxicity Penthorum chinense Pursh
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 2101-2113 doi: 10.1007/s11705-023-2361-5
关键词: ursolic acid antibacterial activities reactive oxygen species apoptosis
Antibacterial properties of extracts of
Manhong YE,Lei ZHANG,Jiaqi GE,Haifeng SUN,Jingjing NI,Shengmei YANG,Wanhong WEI
《农业科学与工程前沿(英文)》 2015年 第2卷 第4期 页码 327-334 doi: 10.15302/J-FASE-2015078
关键词: antibacterial activity Canadian goldenrod antioxidant enzyme crayfish
《环境科学与工程前沿(英文)》 2023年 第17卷 第3期 doi: 10.1007/s11783-023-1631-2
● All 1,4-naphthoquinone hybrids exhibited significant antimicrobial activity.
关键词: 1 4-naphthoquinone derivatives Antibacterial Action mechanism RecA
《化学科学与工程前沿(英文)》 2023年 第17卷 第10期 页码 1544-1554 doi: 10.1007/s11705-022-2288-2
关键词: cellulose-based nanocomposite biodegradable antibacterial fabric nano-copper ions face masks
Estrogenic activities of di-2-ethylhexyl phthalate
JIN Qiumei, LI Yan, SUN Zengrong
《医学前沿(英文)》 2008年 第2卷 第3期 页码 303-308 doi: 10.1007/s11684-008-0058-2
Jianzhong Ma,Li Ma,Lei Zhang,Wenbo Zhang,Qianqian Fan,Buxing Han,
《工程(英文)》 doi: 10.1016/j.eng.2023.06.005
关键词: MXene nanosheets Vanillin Styrene substitute Leather coating Photothermal conversion Warmth retention Antibacterial properties
《化学科学与工程前沿(英文)》 2022年 第16卷 第7期 页码 1090-1100 doi: 10.1007/s11705-021-2091-5
关键词: synthesis pyrimidin-4-amine derivatives 1 2 4-oxadiazole insecticidal activity structure-activity relationship
王礼恒
《中国工程科学》 2008年 第10卷 第12期 页码 10-12
概述了国际航天发展的现状,对国际航天发展的新趋向“新世纪航天新计划”及其特点进行了概括,同时客观地总结了我国航天事业发展所取得的辉煌成就,在此基础上充分地展望了我国航天事业未来的发展愿景。
李佩成
《中国工程科学》 2000年 第2卷 第2期 页码 5-9
总结过去,展望未来,作者提出新世纪人类水事活动的新思维,并用大量事例和数据作了论证,认为在21世纪的水事活动中必须正确处理人类活动、水体动态、生态环境、经济发展与社会进步的关系,简称人-水-环-发-社关系;要特别把握人类水事活动和其它人类活动对水体动态的长期影响及其逆反作用;要把水库视为保护和恢复水源的决定性措施加以实现;正确处理耕地、绿地和水域的关系,保护并适当增大水体面积,保护沼泽,关心小河小水的命运;在未来水事活动中要从与天的抗争转变为适应与利用,充分运用各种信息技术建立“信息水利”,并通过对水文气象的把握,经营“应变农业”,从而在获得足够农产品的同时能在用水量最大的部门求得战略性的节水途径。
孙来燕
《中国工程科学》 2006年 第8卷 第10期 页码 6-12
回顾了中国航天50年来取得的成就,总结了中国航天发展的经验及存在的差距;就国际航天的发展趋势,阐述了我国航天未来的发展战略及重点发展领域。
Soil enzyme activities and their indication for fertility of urban forest soil
SHAN Qihua, YU Yuanchun, ZHANG Jinchi, YU Jian
《环境科学与工程前沿(英文)》 2008年 第2卷 第2期 页码 218-223 doi: 10.1007/s11783-008-0037-5
null
《医学前沿(英文)》 2015年 第9卷 第2期 页码 139-145 doi: 10.1007/s11684-015-0377-z
In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatory cytokines. IL-15 is secreted by multiple types of cells including macrophages, neutrophils and skeletal muscle cells. IL-15 expression is induced in immune cells by endotoxin and in muscle cells by physical exercise. Its transcription is induced by transcription factor NF-κB. IL-15 binds to its receptor that contains three different subunits (α, β and γ) to activate JAK/STAT, PI3K/Akt, IKK/NF-κB and JNK/AP1 pathways in cells. In the regulation of metabolism, IL-15 reduces weight gain without inhibiting food intake in rodents. IL-15 suppresses lipogenesis, stimulates brown fat function, improves insulin sensitivity through weight loss and energy expenditure. In human, circulating IL-15 is negatively associated with body weight. In the immune system, IL-15 stimulates proliferation and differentiation of T cells, NK cells, monocytes and neutrophils. In the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is required. In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance energy expenditure to protect the body from obesity and type 2 diabetes. The mechanism of IL-15 action remains to be fully uncovered in the regulation of energy expenditure.
关键词: inflammation obesity cytokine energy expenditure insulin resistance
Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou
《化学科学与工程前沿(英文)》 2016年 第10卷 第1期 页码 108-119 doi: 10.1007/s11705-016-1553-7
关键词: crude polyphenol extract purified polyphenol extract blueberry antioxidant antitumor immunity
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 1913-1924 doi: 10.1007/s11705-023-2350-8
关键词: inverse opal TiO2 silicon carbide quantum dots quantum dot sensitized photocatalyst type-II charge transfer route
标题 作者 时间 类型 操作
A comparison of the biological activities of ethyl acetate fractions from the stems and leaves of
Zhaolei WANG, Kai JIANG, Qinchao DING, Shujun LIU, Xiaobing DOU, Bin DING
期刊论文
Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated apoptosis mechanism
期刊论文
Antibacterial properties of extracts of
Manhong YE,Lei ZHANG,Jiaqi GE,Haifeng SUN,Jingjing NI,Shengmei YANG,Wanhong WEI
期刊论文
Evaluation of 1,4-naphthoquinone derivatives as antibacterial agents: activity and mechanistic studies
期刊论文
Nano-copper ions assembled cellulose-based composite with antibacterial activity for biodegradable personal
期刊论文
Waterborne Poly(Vanillin-Butyl Acrylate)/MXene Coatings for Leather with Desired Warmth Retention and Antibacterial
Jianzhong Ma,Li Ma,Lei Zhang,Wenbo Zhang,Qianqian Fan,Buxing Han,
期刊论文
Synthesis, insecticidal activities and DFT study of pyrimidin-4-amine derivatives containing the 1,2,4
期刊论文
Soil enzyme activities and their indication for fertility of urban forest soil
SHAN Qihua, YU Yuanchun, ZHANG Jinchi, YU Jian
期刊论文
Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes
null
期刊论文
Antioxidant and antitumor effects and immunomodulatory activities of crude and purified polyphenol extract
Xiaohong Kou,Lihua Han,Xingyuan Li,Zhaohui Xue,Fengjuan Zhou
期刊论文